产品货号：
Z30431
中文名称：
ZEB2抗体
英文名称：
Anti-ZEB2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZEB2 Antibody |
| 指标别名 | KIAA0569;SIP 1;SIP1;Smad interacting protein 1;SMADIP1;ZEB2;ZFHX1B;ZFX1B |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM |
| 基因名称 | ZEB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ZEB2 recombinant protein (Position:M1-P200).Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2. |
| 实际分子量 | 136～200KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ZEB2(Zinc finger E-box-binding homeobox2),also known as SIP1 or ZINC FINGER HOMEOBOX 1B(ZFHX1B),is a protein that in humans is encoded by the ZEB2 gene.The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs,the transducers of TGF-beta signaling,and interacts with the nucleosome remodeling and histone deacetylation(NURD) complex.By radiation hybrid analysis,this gene is mapped to 2q22.It has been found that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines,and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition. |
| Uniprot ID | O60315 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | zinc finger E-box binding homeobox 2 |
| 蛋白名全称 | Zinc finger E-box-binding homeobox 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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